Journal: Frontiers in Physiology
Article Title: Glucose-dependent insulinotropic polypeptide stimulates post-absorptive lipid secretion in the intestine
doi: 10.3389/fphys.2025.1549392
Figure Lengend Snippet: Intraperitoneal administration of GIP increases lymph fluid and TG output from the gut during post-absorptive state. (A) Lymph flow rate, (B) TG concentration and (C) TG output during the experiment, and (D) Total Lymph Volume and Total TG Output during the first hour. Data are mean ± SEM. n = 7 each group. * p < 0.05, ** p < 0.01, *** p < 0.001 GIP vs. PBS.
Article Snippet: 5 h later, rats (n = 7–8 per group) were randomized to receive intraperitoneal infusion of either a long-acting GIP analogue (D-Ala2-GIP, 0.12 mg/kg, in 1 mL PBS; Pepceuticals Ltd., Leicestershire, UK) or placebo (PBS, 1 mL).
Techniques: Concentration Assay